A Well-Tried Tool to Characterize Dyslipidemic Mechanisms

Metabolic studies of lipoproteins have yielded important insights into regulation of energy distribution as well as providing fundamental understanding of cardiovascular risk properties of different lipoproteins. Although many factors on the molecular level have the potential to impact metabolic regulation of lipids, metabolic studies provide valuable information from a comprehensive regulatory viewpoint. With increasing emphasis on lipoprotein subfractions and their roles in promoting or protecting from cardiovascular risk, the focus of metabolic studies is largely moving toward more detailed understanding of lipoprotein subclass and individual apolipoprotein properties.